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Guanosine is a nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond.
Guanosine can be phosphorylated to become GMP (guanosine monophosphate), cGMP (cyclic guanosine monophosphate), GDP (guanosine diphosphate) and GTP (guanosine triphosphate).
When guanine is attached to a deoxyribose ring, it is known as a deoxyguanosine.
Guanosine's structure bears similarities to that of the antiviral drug aciclovir, often used in Herpes treatment.